In-Clinic Monitoring >> Orthostatic measurements taken after supine for a few minutes and again after standing for a few minutes may help identify neurogenic orthostatic hypotension (nOH) in patients.1-3

At-Home Monitoring >> Orthostatic measurements may also be taken at home by the patient to help identify nOH in patients with delayed symptomatic episodes.2,4-6

Excluding Other Causes >> There may be other causes for unexplained symptomatic episodes besides nOH.2,4,7

Specialty Testing >> Specialty tests for diagnosing nOH include, but are not limited to, 24-hour ambulatory blood pressure monitoring and the tilt table test.4,5,8


Some patients with nOH may mistake their nOH symptoms as being associated with their pre-existing neurodegenerative disorder.5 Screening questions may help identify nOH in patients experiencing symptoms upon standing.4,9,10

References: 1. Kaufmann H, Norcliffe-Kaufmann L, Palma JA. Droxidopa in neurogenic orthostatic hypotension. Expert Rev Cardiovasc Ther. 2015;13(8):875-891. 2. Shibao C, Lipsitz LA, Biaggioni I. Evaluation and treatment of orthostatic hypotension. J Am Soc Hypertens. 2013;7(4):317-324. 3. Centers for Disease Control and Prevention. Measuring orthostatic blood pressure. Accessed December 18, 2017. 4. Gibbons CH, Schmidt P, Biaggioni I, et al. The recommendations of a consensus panel for the screening, diagnosis, and treatment of neurogenic orthostatic hypotension and associated supine hypertension. J Neurol. 2017;264(8):1567-1582. 5. Low PA. Neurogenic orthostatic hypotension: pathophysiology and diagnosis. Am J Manag Care. 2015;21(suppl 13):s248-s257. 6. Stuebner E, Vichayanrat E, Low DA, et al. Twenty-four hour non-invasive ambulatory blood pressure and heart rate monitoring in Parkinson’s disease. Front Neurol. 2013;4:49. 7. Goldstein DS, Sharabi Y. Neurogenic orthostatic hypotension: a pathophysiological approach. Circulation. 2009;119(1):139-146. 8. Freeman R. Neurogenic orthostatic hypotension. N Engl J Med. 2008;358(6):615-624. 9. Low PA, Singer W. Management of neurogenic orthostatic hypotension: an update. Lancet Neurol. 2008;7(5):451-458. 10. Kaufmann H, Malamut R, Norcliffe-Kaufmann L, et al. The Orthostatic Hypotension Questionnaire (OHQ): validation of a novel symptom assessment scale. Clin Auton Res. 2012;22(2):79-90.