UNPREDICTABLE SYMPTOMS CONTRIBUTE TO THE VICIOUS CYCLE OF nOH

  • Fear of symptomatic events and related falls may lead patients to reduce physical activity, resulting in physical deconditioning and the exacerbation of neurogenic orthostatic hypotension (nOH) symptoms1-3
  • This may further result in depression, social isolation, and impaired quality of life3

 

“His symptoms totally changed the way that he lived. One minute he was running his own business, he was driving across the state, and then all of a sudden he really couldn't do any of those things.” –Linda, nOH care partner

The Vicious Cycle of nOH

SYMPTOMS OF nOH CAN NEGATIVELY IMPACT SOCIAL AND PHYSICAL FUNCTIONING

Person sitting graphic

Patients with nOH may restrict their activity and lose autonomy due to a fear of symptoms such as dizziness, lightheadedness, and syncope, which can occur at any time of the day, upon standing.1,3

person falling graphic

Feeling dizzy or lightheaded while performing activities of daily living could put patients at increased risk for serious consequences, including falls.3-5

A diagnosis of nOH may provide a path forward for appropriate symptom management.3

REFERENCES
  1. Palma JA, Kaufmann H. Epidemiology, diagnosis, and management of neurogenic orthostatic hypotension. Mov Disord Clin Pract. 2017;4(3):298-308.
  2. Freeman R. Neurogenic orthostatic hypotension. N Engl J Med. 2008;358:615-624.
  3. Low PA. Neurogenic orthostatic hypotension: pathophysiology and diagnosis. Am J Manag Care. 2015;21(suppl 13):s248-s257.
  4. Gibbons CH, Schmidt P, Biaggioni I, et al. The recommendations of a consensus panel for the screening, diagnosis, and treatment of neurogenic orthostatic hypotension and associated supine hypertension. J Neurol. 2017;264(8):1567-1582.
  5. Rascol O, Perez-Lloret S, Damier P, et al. Falls in ambulatory non-demented patients with Parkinson's disease. J Neural Transm. 2015;122:1447-1455.